The Endocannabinoid System, CBD Hemp Oil, & The End Of Suffering

In the last few decades there’s been an unbelievable amount of research into the understanding of something called endocannabinoids.  With that said, right now my spell-checker is currently blinking at me when I right out the word. This just goes to show that although medical science can make leaps and bounds in the light of contemporary research containing cannabis, the stigma still remains. The very word conjures up propaganda films made in the 30’s like ‘Reefer Madness’.  It’s as Max Planck put it, “A new scientific truth does not triumph by convincing opponents and making them see the light, but rather because its opponents eventually die, and a new generation grows up that is familiar with it. Science advances one funeral at a time.”

Scientists coined the name endocannabinoid from its namesake, cannabis, or ‘cannabis sativa’, more popularly known as marijuana.  Endo simply means “within,” and cannabinoids are chemical compounds that do jobs like regulate our mood, temperature, and homeostasis.  We don’t need to smoke weed to get this system; it is an innate part of our physiology, hence the term “endo”; it’s within our body already.

The reason this system is so important is because it’s been found to regulate nearly all parts of the human body.  “Receptors” have been found all over the body, but the two most studied are the CB1 and CB2 receptors which are found primarily in the nervous system and immune system respectively.  But they’re really all over the place and there are more of these receptors still left to be discovered.

It is an established scientific fact that cannabinoids and other components of cannabis can modulate many physiological systems in the human brain and body. Cannabinoids are chemical compounds that trigger cannabinoid (and other) receptors. More than 100 cannabinoids have been identified in the marijuana plant. Of these marijuana molecules, tetrahydrocannabinol (THC) and cannabidiol (CBD) have been studied most extensively. In addition to cannabinoids produced by the plant, there are endogenous cannabinoids (such as anandamide and 2AG) that occur naturally in the mammalian brain and body, as well as synthetic cannabinoids created by pharmaceutical researchers.

There is no shortage of research on this topic.  Doing a search of cannabinoid on the highly accredited website of The National Library of Medicine ( reveals nearly 20,000 hits. This is not some website of some ranty blogger sitting in the basement of his mom’s house; this is some of the most highly respected and peer reviewed medical research out there.


“Modulating the activity of the endocannabinoid system turned out to hold therapeutic promise in a wide range of disparate diseases and pathological conditions, ranging from mood and anxiety disorders, movement disorders such as Parkinson’s and Huntington’s disease, neuropathic pain, multiple sclerosis and spinal cord injury, to cancer, atherosclerosis, myocardial infarction, stroke, hypertension, glaucoma, obesity/metabolic syndrome, and osteoporosis, to name just a few. “

“The ability of extracts of the hemp plant (Cannabis sativa) to cause a variety of medicinal effects unrelated to its psychoactive properties had been recognized as early as the third millennium BC.”

-The National Library of Medicine (The Endocannabinoid System as an Emerging Target of Pharmacotherapy)


We’ve long known that olive oil is a healthy.  But only recently have we learned that it’s the endocannabinoid system (ECS) which mediates this therapeutic affect.  This is just one example of how this system is an inherent part of healing and wellness.  We are learning more and more everyday about the health benefits of the cannabinoids that are found in cannabis and hemp.

You might be familiar with CBD oil that is made from hemp. Most, if not all of the brands you come across are merely isolates of CBD, which is one cannabinoid of the plant.  They usually mix it with coconut oil and call it CBD oil, which is fine because that is what they are selling.  The only problem with that is, it doesn’t really work as well as the real thing, which is pure Cannabis or Hemp Oil, with all of the 100+ cannabinoids, and not just the one.


The Entourage Effect

The reason CBD (cannabidoil) is so popular is because that is what has been studied the most, however it is just one chemical compound of many found in cannabis and they all work synergistically together.  This has been called the “entourage effect”.

“A large part of alternative medicine is based on using the entire plant for medicinal purposes rather than isolating or producing the active ingredient in a laboratory. It’s called whole plant medicine, and herbalists excel at matching holistic, plant-based treatments to a variety of ailments. In a world inundated with Western medicine, pills, and quick fixes, this approach may seem old-fashioned, but mounting evidence suggests that medical substances may be more effective in plant form than in pill form.

This phenomenon, called the “entourage effect,” results when hundreds of natural components within a plant interact together and with the human body to produce a stronger influence than any one of those components used alone. It’s a synergistic effect. When we combine multiple compounds in their natural state, we don’t end up with the sum of the parts; we get a multiplying effect instead. The different compounds can amplify each other’s effects, making the overall plant more effective in treating the unwanted medical symptoms.”


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Granny Storm Crow’s List

“If the truth won’t do, then something is wrong!”

“Those were the furious words of my Grandfather to my Mother. I had walked in from joyfully stuffing my face with red raspberries in the garden, straight into “war zone”! My gentle Grandfather in a fury, his hand raised! Mom was just beginning to shrink back away from him. They saw me and quickly sent me away. But it was too late, the scene and the words were seared into my 5-year-old brain. That was over 55 years ago, but I still remember it clearly. My Grandfather was a Minister, one very short step away from God in my young mind. It was one of those life changing moments. It is still rare for me to tell a lie. I never found out what my Mother’s lie was.

As I child, I suffered a traumatic head injury. Another child tried to murder me with a hammer. I was left with frequent migraines. At 19, like many rebellious teens, I tried cannabis. It took about a year for me to make the connection between using cannabis and the absence of my normally frequent migraines. I have used cannabis ever since.

I am an avid reader. While perusing an old book on herbal medicine, I read how the little old ladies of Mexico made and used a cannabis/tequila rub on their arthritic hands. Then I met Joey, an epileptic musician. He told me another interesting fact – when he had pot he could cut his medication in half! On a camping trip years later, I smelled an unmistakable odour. Following my nose, I was totally shocked to find a grandmotherly lady in her 70s puffing away on a delicate oriental pipe. “Parkinson’s. And the pot’s way cheaper than the pills!” Her nephew kept her well supplied, she said. We had a nice chat about various medical uses of cannabis.

Epilepsy, Parkinson’s, Arthritis, and my Migraines! What else was it good for? Yet every news article on cannabis that I saw, claimed one new horror after another. Men grew breasts and were impotent. Women became sterile, or miscarried. It made you crazy and murderous. Made you lazy and do nothing. It caused cancer and heart attacks…What I had learned on my own and from others and what I was being told in the press were so different!

What was the truth? I began researching. I printed the first studies up and kept them in a notebook, just as a personal reference. The notebook quickly filled. I started a Word file of the URLs and on July 30 2007, I posted it. It continues to grow.

Here’s some of what I have found. All I’ve done is copy the URLs, then put them all in some semblance order for everyone to use as a reference. Please feel free to share this list with anyone who could benefit from it.

The List is here as a gateway to your education about cannabis, not an endpoint. Because of the irrational prohibition of cannabis, we are only beginning to understand the potential of this pleasant, healing herb. Already, our fascination with cannabis and its “high” has led to a completely new, major branch of medical science, the study of the endocannabinoid system.”  -Granny Storm Crow

Granny Storm Crow’s List – WordPress 

Granny Storm Crow’s List (January 2017) – The PDF (3753 pages of peer reviewed studies and articles) (download this)


Disclaimer: This site pro­vides gen­eral infor­ma­tion and dis­cus­sion about med­i­cine, health and related sub­jects. The words and other con­tent pro­vided in this article, and in any linked mate­ri­als, are not intended and should not be con­strued as med­ical advice. If the reader or any other per­son has a med­ical con­cern, he or she should con­sult with an appropriately-licensed physi­cian or other health care worker. Noth­ing con­tained in the website is intended to estab­lish a physician-patient rela­tion­ship, to replace the ser­vices of a badly trained allopathic physi­cian or health care pro­fes­sional, or oth­er­wise to be a sub­sti­tute for pro­fes­sional med­ical advice, diag­no­sis, or treatment. There is no better person to take care of yourself than yourself.  Find out the truth for yourself. Use your common sense.  Use your intuition.


International Cannabinoid Research Society

Project CBD

NORML – Intro into the Endocannabinoid System

Cannabis Wins

Hemp Health Youtube Playlist

Leafly Health

ABoulderPharm (Coupon code JW1017 10% off)

More Studies – Hemp Health

Beginner’s Guide To The Endocannabinoid System — The Reason Our Bodies So Easily Process Cannabis

Health Benefits of Hemp – Mercola

Medical Marijuana and Epilepsy –

Charlotte’s Web – Marijuana Stops Child’s Seizures – CNN story

Illegally Healed – Patient Success Stories

Studied Benefits Of CBD For Your Health – A Boulder Pharm


Now Selling on! CBD Hemp Oil (Full Spectrum-Whole Plant Cannabis Extract)

Joe Dubs

I write about philosophy, geometry, health, politics and other stuff that interests me.


  1. If you use the entire oil or 100% oil, will I still have a clean UA or is there THC in the 100% hemp oil?

    • It is highly unlikely, but it is possible if you take the whole bottle at once. One 1oz bottle is supposed to last at least a month with daily usage. So, It is hardly possible, but theoretically it is possible.

  2. CBD Oil helps in insomnia, chronic pain, cancer related issues and much more. I have used it for my insomnia and it is helpful. I used to take on;y 1 dropper as my dr suggested. But I keep reading about CBD so that It can help me more. Your article will surely help me. Thanks!!

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